3coh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3coh is ON HOLD Authors: Wiesmann, C., Raswson, T.E., Cochran, A.G. Description: Crystal structure of Aurora-A in complex with a pentacyclic inhibi...) |
|||
| Line 1: | Line 1: | ||
| - | + | {{Seed}} | |
| + | [[Image:3coh.jpg|left|200px]] | ||
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3coh", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3coh| PDB=3coh | SCENE= }} | ||
| - | + | ===Crystal structure of Aurora-A in complex with a pentacyclic inhibitor=== | |
| - | Description: Crystal structure of Aurora-A in complex with a pentacyclic inhibitor | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_18630890}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 18630890 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_18630890}} | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ==About this Structure== |
| + | 3COH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COH OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:18630890</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Cochran, A G.]] | ||
| + | [[Category: Raswson, T E.]] | ||
| + | [[Category: Wiesmann, C.]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Aurora-a]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Inhibitor complex]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Transferase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:07:32 2009'' | ||
Revision as of 07:07, 18 February 2009
Crystal structure of Aurora-A in complex with a pentacyclic inhibitor
Template:ABSTRACT PUBMED 18630890
About this Structure
3COH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rawson TE, Ruth M, Blackwood E, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Georges GJ, Goller B, Halladay J, Hunsaker T, Kleinheinz T, Krell HW, Li J, Liang J, Limberg A, McNutt A, Moffat J, Phillips G, Ran Y, Safina B, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhou A, Zhu BY, Ruger P, Cochran AG. A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability. J Med Chem. 2008 Aug 14;51(15):4465-75. Epub 2008 Jul 17. PMID:18630890 doi:10.1021/jm800052b
Page seeded by OCA on Wed Feb 18 09:07:32 2009
