3dv1

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(New page: '''Unreleased structure''' The entry 3dv1 is ON HOLD until Paper Publication Authors: Rondeau, J.-M. Description: Crystal structure of human beta-secretase in complex with NVP-ARV999 ...)
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'''Unreleased structure'''
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[[Image:3dv1.jpg|left|200px]]
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The entry 3dv1 is ON HOLD until Paper Publication
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{{STRUCTURE_3dv1| PDB=3dv1 | SCENE= }}
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Authors: Rondeau, J.-M.
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===Crystal structure of human beta-secretase in complex with NVP-ARV999===
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Description: Crystal structure of human beta-secretase in complex with NVP-ARV999
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 6 12:30:29 2008''
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{{ABSTRACT_PUBMED_19195887}}
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==About this Structure==
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3DV1 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DV1 OCA].
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==Reference==
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<ref group="xtra">PMID:19195887</ref><ref group="xtra">PMID:19195886</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Rondeau, J M.]]
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[[Category: Alternative splicing]]
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[[Category: Alzheimer's disease]]
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[[Category: Aspartic protease]]
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[[Category: Aspartyl protease]]
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[[Category: Bace1]]
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[[Category: Beta-secretase]]
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[[Category: Enzyme inhibitor complex]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Memapsin2]]
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[[Category: Membrane]]
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[[Category: Transmembrane]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 25 09:29:29 2009''

Revision as of 07:29, 25 February 2009

Template:STRUCTURE 3dv1

Crystal structure of human beta-secretase in complex with NVP-ARV999

Template:ABSTRACT PUBMED 19195887

About this Structure

3DV1 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U. Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. Epub 2009 Jan 22. PMID:19195887 doi:10.1016/j.bmcl.2009.01.055
  • Machauer R, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Neumann U, Paganetti P. Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1361-5. Epub 2009 Jan 19. PMID:19195886 doi:10.1016/j.bmcl.2009.01.036

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