3dv1
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3dv1 is ON HOLD until Paper Publication Authors: Rondeau, J.-M. Description: Crystal structure of human beta-secretase in complex with NVP-ARV999 ...) |
|||
Line 1: | Line 1: | ||
- | + | {{Seed}} | |
+ | [[Image:3dv1.jpg|left|200px]] | ||
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3dv1", creates the "Structure Box" on the page. | ||
+ | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
+ | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
+ | or leave the SCENE parameter empty for the default display. | ||
+ | --> | ||
+ | {{STRUCTURE_3dv1| PDB=3dv1 | SCENE= }} | ||
- | + | ===Crystal structure of human beta-secretase in complex with NVP-ARV999=== | |
- | Description: Crystal structure of human beta-secretase in complex with NVP-ARV999 | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
+ | The line below this paragraph, {{ABSTRACT_PUBMED_19195887}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 19195887 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_19195887}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | 3DV1 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DV1 OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:19195887</ref><ref group="xtra">PMID:19195886</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Memapsin 2]] | ||
+ | [[Category: Rondeau, J M.]] | ||
+ | [[Category: Alternative splicing]] | ||
+ | [[Category: Alzheimer's disease]] | ||
+ | [[Category: Aspartic protease]] | ||
+ | [[Category: Aspartyl protease]] | ||
+ | [[Category: Bace1]] | ||
+ | [[Category: Beta-secretase]] | ||
+ | [[Category: Enzyme inhibitor complex]] | ||
+ | [[Category: Glycoprotein]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Memapsin2]] | ||
+ | [[Category: Membrane]] | ||
+ | [[Category: Transmembrane]] | ||
+ | [[Category: Zymogen]] | ||
+ | |||
+ | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 25 09:29:29 2009'' |
Revision as of 07:29, 25 February 2009
Crystal structure of human beta-secretase in complex with NVP-ARV999
Template:ABSTRACT PUBMED 19195887
About this Structure
3DV1 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U. Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. Epub 2009 Jan 22. PMID:19195887 doi:10.1016/j.bmcl.2009.01.055
- Machauer R, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Neumann U, Paganetti P. Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1361-5. Epub 2009 Jan 19. PMID:19195886 doi:10.1016/j.bmcl.2009.01.036
Page seeded by OCA on Wed Feb 25 09:29:29 2009