Rebecca Martin/Sandbox1

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{{STRUCTURE_3cm9 | PDB=3cm9 | SCENE= IgA1}}
{{STRUCTURE_3cm9 | PDB=3cm9 | SCENE= IgA1}}
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<applet load='1r70' size='300' frame='true' align='right' caption='IgA2' /> <applet load='1iga' size='300' frame='true' align='right' caption='IgA1' />
<applet load='1r70' size='300' frame='true' align='right' caption='IgA2' /> <applet load='1iga' size='300' frame='true' align='right' caption='IgA1' />
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== Secretory Component and Polyimmunoglobulin receptor ==
== Secretory Component and Polyimmunoglobulin receptor ==
<applet load='2ocw' size='150' frame='true' align='left' caption='This is the secretory component.' />
<applet load='2ocw' size='150' frame='true' align='left' caption='This is the secretory component.' />
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Revision as of 13:53, 22 April 2009

Contents

Introduction

IgA1

Template:STRUCTURE 3cm9































General Structure

  • Antibody Structure
  • Dimeric Structure

  • Secretory Component


IgA1 and IgA2

IgA2

Drag the structure with the mouse to rotate

IgA1

Drag the structure with the mouse to rotate





























Secretory Component and Polyimmunoglobulin receptor

This is the secretory component.

Drag the structure with the mouse to rotate




























Insights into Function

Evolution

Implications in Science and Medicine

Limitations of the Current Studies

Questions for the Future

Links

IgA

  • Model of human IgA1 determined by solution scattering, curve-fitting, and homology modeling 1iga
  • Model of human IgA2 determined by solution scattering, curve fitting and homology modelling 1r70
  • Crystal structure of human FcaRI bound to IgA1-Fc 1ow0
  • Solution structure of human dimeric immunoglobulin A 2qtj
  • Solution structure of human secretory IgA1 3chn
  • Solution Structure of Human SIgA2 3cm9
  • Solution structure of human secretory component 2ocw

Receptors

  • Crystal Structure of a Ligand-Binding Domain of the Human Polymeric Ig Receptor, pIgR 1XED
  • Crystal structure of human FcaRI 10vz
  • Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 2qej

For Comparison

  • IgM: Solution structure of human Immunoglobulin M 2rcj
  • IgG:
  • IgD:
  • IgE:


References

Proteopedia Page Contributors and Editors (what is this?)

Rebecca Martin, Jaime Prilusky

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