3ehx

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ehx.jpg|left|200px]]
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The entry 3ehx is ON HOLD until Paper Publication
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{{STRUCTURE_3ehx| PDB=3ehx | SCENE= }}
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Authors: Dragoni, E., Calderone, V., Fragai, M., Jaiswal, R., Luchinat, C., Nativi, C.
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===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid===
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Description: Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:19:42 2008''
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{{ABSTRACT_PUBMED_19275207}}
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==About this Structure==
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3EHX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EHX OCA].
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==Reference==
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<ref group="xtra">PMID:19275207</ref><ref group="xtra">PMID:12813751</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Macrophage elastase]]
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[[Category: Calderone, V.]]
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[[Category: Calcium]]
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[[Category: Elastase]]
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[[Category: Extracellular matrix]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Matrix metalloproteinase]]
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[[Category: Metal-binding]]
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[[Category: Metallo elastase]]
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[[Category: Metalloprotease]]
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[[Category: Mmp12]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Zinc]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 17:02:36 2009''

Revision as of 14:02, 20 May 2009

Template:STRUCTURE 3ehx

Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid

Template:ABSTRACT PUBMED 19275207

About this Structure

3EHX is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dragoni E, Calderone V, Fragai M, Jaiswal R, Luchinat C, Nativi C. Biotin-tagged probes for MMP expression and activation: design, synthesis, and binding properties. Bioconjug Chem. 2009 Apr;20(4):719-27. PMID:19275207 doi:10.1021/bc8003827
  • Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B. X-ray structures of binary and ternary enzyme-product-inhibitor complexes of matrix metalloproteinases. Angew Chem Int Ed Engl. 2003 Jun 16;42(23):2673-6. PMID:12813751 doi:10.1002/anie.200350957

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