3g0x

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3g0x.jpg|left|200px]]
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The entry 3g0x is ON HOLD until Paper Publication
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{{STRUCTURE_3g0x| PDB=3g0x | SCENE= }}
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Authors: Davies, M., Heikkila, T., McConkey, G.A., Fishwick, C.W.G., Parsons, M.R., Johnson, A.P.
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===Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5===
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Description: Design and Synthesis of Potent Inhibitors of the Malaria Parasite Dihydroorotate Dehydrogenase
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 4 14:42:58 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19351152 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19351152}}
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==About this Structure==
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3G0X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0X OCA].
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==Reference==
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<ref group="xtra">PMID:19351152</ref><references group="xtra"/>
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[[Category: Dihydroorotate oxidase]]
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[[Category: Homo sapiens]]
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[[Category: Davies, M.]]
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[[Category: Fishwick, C W.G.]]
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[[Category: Heikkila, T.]]
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[[Category: Johnson, A P.]]
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[[Category: McConkey, G A.]]
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[[Category: Parsons, M R.]]
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[[Category: Beta barrel]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Membrane]]
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[[Category: Mitochondrion]]
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[[Category: Mitochondrion inner membrane]]
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[[Category: Oxidoreductase]]
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[[Category: Polymorphism]]
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[[Category: Pyrimidine biosynthesis]]
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[[Category: Tim barrel]]
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[[Category: Transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:03:32 2009''

Revision as of 15:03, 10 June 2009

Image:3g0x.jpg

Template:STRUCTURE 3g0x

Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5

Template:ABSTRACT PUBMED 19351152

About this Structure

3G0X is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Davies M, Heikkila T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93. PMID:19351152 doi:10.1021/jm800963t

Page seeded by OCA on Wed Jun 10 18:03:32 2009

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