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3gdh

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Revision as of 13:21, 29 July 2009

Image:3gdh.png

Template:STRUCTURE 3gdh

Methyltransferase domain of human Trimethylguanosine Synthase 1 (TGS1) bound to m7GTP and adenosyl-homocysteine (active form)

Template:ABSTRACT PUBMED 19386620

About this Structure

3GDH is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Monecke T, Dickmanns A, Ficner R. Structural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1. Nucleic Acids Res. 2009 Jul;37(12):3865-77. Epub 2009 Apr 22. PMID:19386620 doi:10.1093/nar/gkp249

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