1gwc
From Proteopedia
(New page: 200px<br /> <applet load="1gwc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gwc, resolution 2.25Å" /> '''THE STRUCTURE OF A ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1GWC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Aegilops_tauschii Aegilops tauschii]] with SO4 and GTX as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWC OCA]]. | + | 1GWC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Aegilops_tauschii Aegilops tauschii]] with SO4 and GTX as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Transferase Transferase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWC OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: tau class]] | [[Category: tau class]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:33:30 2007'' |
Revision as of 06:28, 30 October 2007
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THE STRUCTURE OF A TAU CLASS GLUTATHIONE S-TRANSFERASE FROM WHEAT, ACTIVE IN HERBICIDE DETOXIFICATION
Overview
Glutathione S-transferases (GSTs) from the phi (GSTF) and tau (GSTU), classes are unique to plants and play important roles in stress tolerance, and secondary metabolism as well as catalyzing the detoxification of, herbicides in crops and weeds. We have cloned and functionally, characterized a group of GSTUs from wheat treated with, fenchlorazole-ethyl, a herbicide safener. One of these enzymes, TaGSTU4-4, was highly active in conjugating the chemically distinct wheat herbicides, fenoxaprop and dimethenamid. The structure of TaGSTU4-4 has been, determined at 2.2 A resolution in complex with S-hexylglutathione. This, enzyme is the first tau class GST structure to be determined and most, closely resembles the omega class GSTs, but without the unique N-terminal, extension or active site ... [(full description)]
About this Structure
1GWC is a [Single protein] structure of sequence from [Aegilops tauschii] with SO4 and GTX as [ligands]. Active as [Transferase], with EC number [2.5.1.18]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Structure of a tau class glutathione S-transferase from wheat active in herbicide detoxification., Thom R, Cummins I, Dixon DP, Edwards R, Cole DJ, Lapthorn AJ, Biochemistry. 2002 Jun 4;41(22):7008-20. PMID:12033934
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