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3gpw

From Proteopedia

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3gpw.jpg|left|200px]]
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The entry 3gpw is ON HOLD until Paper Publication
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{{STRUCTURE_3gpw| PDB=3gpw | SCENE= }}
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Authors: Groll, M., Macherla, V.R., Manam, R.R., Arthur, K.A.M., Potts, C.B.
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===Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand===
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Description: Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:08:21 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19678642 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19678642}}
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==About this Structure==
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3GPW is a 28 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GPW OCA].
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==Reference==
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<ref group="xtra">PMID:19678642</ref><references group="xtra"/>
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[[Category: Proteasome endopeptidase complex]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Arthur, K A.M.]]
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[[Category: Groll, M.]]
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[[Category: Macherla, V R.]]
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[[Category: Manam, R R.]]
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[[Category: Potts, C B.]]
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[[Category: Cancer therapy]]
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[[Category: Cytoplasm]]
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[[Category: Hydrolase]]
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[[Category: Immunology]]
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[[Category: Isopeptide bond]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Protease]]
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[[Category: Proteasome]]
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[[Category: Threonine protease]]
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[[Category: Time-dependent elimination of a defined leaving group]]
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[[Category: Ubiquitin]]
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[[Category: Ubl conjugation]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 09:02:11 2009''

Revision as of 06:02, 16 September 2009

Image:3gpw.jpg

Template:STRUCTURE 3gpw

Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand

Template:ABSTRACT PUBMED 19678642

About this Structure

3GPW is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x

Page seeded by OCA on Wed Sep 16 09:02:11 2009

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