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3ghc

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ghc.jpg|left|200px]]
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The entry 3ghc is ON HOLD until Paper Publication
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{{STRUCTURE_3ghc| PDB=3ghc | SCENE= }}
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Authors: Cody, V.
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===Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-amino-4-oxo-5-substituted-6-thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agenst===
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Description: Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-amino-4-oxo-5-substituted-6-thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agenst
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 09:13:24 2009''
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{{ABSTRACT_PUBMED_19719239}}
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==About this Structure==
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3GHC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GHC OCA].
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==Reference==
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<ref group="xtra">PMID:19719239</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Homo sapiens]]
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[[Category: Cody, V.]]
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[[Category: Nadp]]
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[[Category: One-carbon metabolism]]
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[[Category: Oxidoreductase]]
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[[Category: Protein inhibitor complex folate analogue]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:43:08 2009''

Revision as of 05:43, 23 September 2009

Image:3ghc.jpg

Template:STRUCTURE 3ghc

Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-amino-4-oxo-5-substituted-6-thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agenst

Template:ABSTRACT PUBMED 19719239

About this Structure

3GHC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gangjee A, Li W, Kisliuk RL, Cody V, Pace J, Piraino J, Makin J. Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. J Med Chem. 2009 Aug 13;52(15):4892-902. PMID:19719239 doi:10.1021/jm900490a

Page seeded by OCA on Wed Sep 23 08:43:08 2009

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