3env

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{{Seed}}
 
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[[Image:3env.jpg|left|200px]]
 
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==Substrate and inhibitor complexes of ribose 5-phosphate isomerase from Vibrio vulnificus YJ016==
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The line below this paragraph, containing "STRUCTURE_3env", creates the "Structure Box" on the page.
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<StructureSection load='3env' size='340' side='right'caption='[[3env]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3env]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus Vibrio vulnificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ENV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABF:BETA-D-ARABINOFURANOSE-5-PHOSPHATE'>ABF</scene></td></tr>
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{{STRUCTURE_3env| PDB=3env | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3env FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3env OCA], [https://pdbe.org/3env PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3env RCSB], [https://www.ebi.ac.uk/pdbsum/3env PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3env ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPIA_VIBVY RPIA_VIBVY]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/3env_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3env ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Ribose-5-phosphate isomerase A (RpiA) plays an important role in interconverting between ribose-5-phosphate (R5P) and ribulose-5-phosphate in the pentose phosphate pathway and the Calvin cycle. We have determined the crystal structures of the open form RpiA from Vibrio vulnificus YJ106 (VvRpiA) in complex with the R5P and the closed form with arabinose-5-phosphate (A5P) in parallel with the apo VvRpiA at 2.0 A resolution. VvRpiA is highly similar to Eschericihia coliRpiA, and the VvRpiA-R5P complex strongly resembles the E. coli RpiA-A5P complex. Interestingly, unlike the E. coli RpiA-A5P complex, the position of A5P in the VvRpiA-A5P complex reveals a different position than the R5P binding mode. VvRpiA-A5P has a sugar ring inside the binding pocket and a phosphate group outside the binding pocket: By contrast, the sugar ring of A5P interacts with the Asp4, Lys7, Ser30, Asp118, and Lys121 residues; the phosphate group of A5P interacts with two water molecules, W51 and W82.
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===Substrate and inhibitor complexes of ribose 5-phosphate isomerase from Vibrio vulnificus YJ016===
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Crystal structures of substrate and inhibitor complexes of ribose 5-phosphate isomerase A from Vibrio vulnificus YJ016.,Kim TG, Kwon TH, Min K, Dong MS, Park YI, Ban C Mol Cells. 2009 Jan;27(1):99-103. Epub 2009 Feb 5. PMID:19214439<ref>PMID:19214439</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3env" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_19214439}}, adds the Publication Abstract to the page
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*[[Ribose-5-phosphate isomerase 3D structures|Ribose-5-phosphate isomerase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 19214439 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_19214439}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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3ENV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_vulnificus Vibrio vulnificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENV OCA].
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==Reference==
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<ref group="xtra">PMID:19214439</ref><references group="xtra"/>
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[[Category: Ribose-5-phosphate isomerase]]
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[[Category: Vibrio vulnificus]]
[[Category: Vibrio vulnificus]]
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[[Category: Kim, T G.]]
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[[Category: Kim TG]]
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[[Category: Kwon, T H.]]
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[[Category: Kwon TH]]
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[[Category: Min, K.]]
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[[Category: Min K]]
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[[Category: Arabinose 5-phosphate]]
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[[Category: Isomerase]]
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[[Category: Ribose 5-phosphate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:20:33 2009''
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Current revision

Substrate and inhibitor complexes of ribose 5-phosphate isomerase from Vibrio vulnificus YJ016

PDB ID 3env

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