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3f01

From Proteopedia

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{{Seed}}
 
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[[Image:3f01.jpg|left|200px]]
 
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==Crystal Structure of Synaptotagmin I C2A domain with Cu(II)==
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The line below this paragraph, containing "STRUCTURE_3f01", creates the "Structure Box" on the page.
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<StructureSection load='3f01' size='340' side='right'caption='[[3f01]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3f01]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F01 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3f01| PDB=3f01 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f01 OCA], [https://pdbe.org/3f01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f01 RCSB], [https://www.ebi.ac.uk/pdbsum/3f01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f01 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYT1_HUMAN SYT1_HUMAN] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/3f01_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f01 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Synaptotagmin I C2A domain with Cu(II)===
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==See Also==
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*[[Synaptotagmin 3D structures|Synaptotagmin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3F01 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F01 OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dakshinamurthy, R.]]
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[[Category: Large Structures]]
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[[Category: Guo, F.]]
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[[Category: Dakshinamurthy R]]
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[[Category: Sakon, J.]]
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[[Category: Guo F]]
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[[Category: Thallapuranam, S K.K.]]
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[[Category: Sakon J]]
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[[Category: C2a]]
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[[Category: Thallapuranam SKK]]
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[[Category: Calcium]]
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[[Category: Cell junction]]
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[[Category: Copper]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Glycoprotein]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Metal binding protein]]
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[[Category: Metal-binding]]
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[[Category: Palmitate]]
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[[Category: Phosphoprotein]]
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[[Category: Synapse]]
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[[Category: Synaptotagmin i]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 14:08:46 2009''
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Current revision

Crystal Structure of Synaptotagmin I C2A domain with Cu(II)

PDB ID 3f01

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