3g8t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:53, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3g8t.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P==
-
The line below this paragraph, containing "STRUCTURE_3g8t", creates the "Structure Box" on the page.
+
<StructureSection load='3g8t' size='340' side='right'caption='[[3g8t]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3g8t]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G8T FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=GLP:GLUCOSAMINE+6-PHOSPHATE'>GLP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_3g8t| PDB=3g8t | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g8t OCA], [https://pdbe.org/3g8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g8t RCSB], [https://www.ebi.ac.uk/pdbsum/3g8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g8t ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/3g8t_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g8t ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P===
+
==See Also==
-
 
+
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
-
 
+
*[[Ribozyme 3D structures|Ribozyme 3D structures]]
-
<!--
+
== References ==
-
The line below this paragraph, {{ABSTRACT_PUBMED_19228039}}, adds the Publication Abstract to the page
+
<references/>
-
(as it appears on PubMed at http://www.pubmed.gov), where 19228039 is the PubMed ID number.
+
__TOC__
-
-->
+
</StructureSection>
-
{{ABSTRACT_PUBMED_19228039}}
+
-
 
+
-
==About this Structure==
+
-
3G8T is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8T OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:19228039</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Cochrane, J C.]]
+
[[Category: Large Structures]]
-
[[Category: Lipchock, S V.]]
+
[[Category: Synthetic construct]]
-
[[Category: Smith, K D.]]
+
[[Category: Cochrane JC]]
-
[[Category: Strobel, S A.]]
+
[[Category: Lipchock SV]]
-
[[Category: Acetylation]]
+
[[Category: Smith KD]]
-
[[Category: Catalytic rna]]
+
[[Category: Strobel SA]]
-
[[Category: Mrna processing]]
+
-
[[Category: Mrna splicing]]
+
-
[[Category: Nucleus]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Ribonucleoprotein]]
+
-
[[Category: Rna binding protein/rna complex]]
+
-
[[Category: Rna-binding]]
+
-
[[Category: Spliceosome]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 4 10:56:01 2009''
+

Current revision

Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P

PDB ID 3g8t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3g8t"
Personal tools