2wb3

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{{Seed}}
 
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[[Image:2wb3.png|left|200px]]
 
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==The partial structure of a group A streptococcal phage-encoded tail fibre hyaluronate lyase Hylp3==
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The line below this paragraph, containing "STRUCTURE_2wb3", creates the "Structure Box" on the page.
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<StructureSection load='2wb3' size='340' side='right'caption='[[2wb3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2wb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WB3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wb3 OCA], [https://pdbe.org/2wb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wb3 RCSB], [https://www.ebi.ac.uk/pdbsum/2wb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wb3 ProSAT]</span></td></tr>
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{{STRUCTURE_2wb3| PDB=2wb3 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q99Z19_STRP1 Q99Z19_STRP1]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wb3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wb3 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structures of truncated forms of the Streptococcus pyogenes phage-encoded hyaluronate lyases HylP2 and HylP3 were determined by molecular replacement to 1.6 and 1.9 A resolution, respectively. The truncated forms crystallized in a hexagonal space group, forming a trimer around the threefold crystallographic axis. The arrangement of the fold is very similar to that observed in the structure of the related hyaluronate lyase HylP1. The structural elements putatively involved in substrate recognition are found to be conserved in both the HylP2 and HylP3 fragments.
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===THE PARTIAL STRUCTURE OF A GROUP A STREPTOCOCCAL PHAGE-ENCODED TAIL FIBRE HYALURONATE LYASE HYLP3===
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Structures of two truncated phage-tail hyaluronate lyases from Streptococcus pyogenes serotype M1.,Martinez-Fleites C, Smith NL, Turkenburg JP, Black GW, Taylor EJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt, 10):963-6. Epub 2009 Sep 18. PMID:19850999<ref>PMID:19850999</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2wb3" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_19850999}}, adds the Publication Abstract to the page
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*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 19850999 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_19850999}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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2WB3 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WB3 OCA].
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==Reference==
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<ref group="xtra">PMID:19850999</ref><references group="xtra"/>
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[[Category: Hyaluronate lyase]]
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[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
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[[Category: Black, G W.]]
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[[Category: Black GW]]
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[[Category: Martinez-Fleites, C.]]
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[[Category: Martinez-Fleites C]]
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[[Category: Smith, N L.]]
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[[Category: Smith NL]]
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[[Category: Taylor, E J.]]
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[[Category: Taylor EJ]]
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[[Category: Turkenburg, J P.]]
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[[Category: Turkenburg JP]]
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[[Category: Hyaluronan lyase]]
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[[Category: Hyaluronidase]]
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[[Category: Lyase]]
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[[Category: Phage tail fibre]]
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[[Category: Scarlet fever]]
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[[Category: Triple-stranded beta- helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 4 12:09:02 2009''
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Current revision

The partial structure of a group A streptococcal phage-encoded tail fibre hyaluronate lyase Hylp3

PDB ID 2wb3

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