3k6l

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{{Seed}}
 
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[[Image:3k6l.jpg|left|200px]]
 
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==The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827==
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The line below this paragraph, containing "STRUCTURE_3k6l", creates the "Structure Box" on the page.
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<StructureSection load='3k6l' size='340' side='right'caption='[[3k6l]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3k6l]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K6L FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2BB:(2S,3R)-N~4~-[(1S)-1-(DIMETHYLCARBAMOYL)-2,2-DIMETHYLPROPYL]-N~1~,2-DIHYDROXY-3-(2-METHYLPROPYL)BUTANEDIAMIDE'>2BB</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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{{STRUCTURE_3k6l| PDB=3k6l | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6l OCA], [https://pdbe.org/3k6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k6l RCSB], [https://www.ebi.ac.uk/pdbsum/3k6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k6l ProSAT]</span></td></tr>
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</table>
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===The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827===
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== Function ==
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[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3K6L is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6L OCA].
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Check<jmol>
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[[Category: Escherichia coli k-12]]
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<jmolCheckbox>
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[[Category: Peptide deformylase]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/3k6l_consurf.spt"</scriptWhenChecked>
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[[Category: Barker, J.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Cheng, R K.Y.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Crawley, L.]]
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</jmolCheckbox>
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[[Category: Felicetti, B.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k6l ConSurf].
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[[Category: Whittaker, M.]]
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<div style="clear:both"></div>
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[[Category: Wood, M.]]
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__TOC__
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[[Category: Ion binding]]
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</StructureSection>
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[[Category: Iron]]
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[[Category: Escherichia coli K-12]]
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[[Category: Metal-binding]]
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[[Category: Large Structures]]
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[[Category: Protein biosynthesis]]
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[[Category: Barker J]]
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[[Category: Translation]]
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[[Category: Cheng RKY]]
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[[Category: Crawley L]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 22:37:45 2009''
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[[Category: Felicetti B]]
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[[Category: Whittaker M]]
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[[Category: Wood M]]

Current revision

The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827

PDB ID 3k6l

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