3jti
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution== | |
+ | <StructureSection load='3jti' size='340' side='right'caption='[[3jti]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[3jti]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTI FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jti FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jti OCA], [https://pdbe.org/3jti PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jti RCSB], [https://www.ebi.ac.uk/pdbsum/3jti PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jti ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PA2A3_NAJSG PA2A3_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jti_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jti ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | + | ==See Also== | |
- | + | *[[Amyloid precursor protein 3D structures|Amyloid precursor protein 3D structures]] | |
- | + | *[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Naja sagittifera]] | ||
+ | [[Category: Bhushan A]] | ||
+ | [[Category: Kaur P]] | ||
+ | [[Category: Mirza Z]] | ||
+ | [[Category: Pandey N]] | ||
+ | [[Category: Sharma S]] | ||
+ | [[Category: Singh N]] | ||
+ | [[Category: Singh TP]] | ||
+ | [[Category: Srinivasan A]] | ||
+ | [[Category: Vikram G]] |
Current revision
Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution
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Categories: Homo sapiens | Large Structures | Naja sagittifera | Bhushan A | Kaur P | Mirza Z | Pandey N | Sharma S | Singh N | Singh TP | Srinivasan A | Vikram G