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3kl4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3kl4 is ON HOLD Authors: Janda, C.Y., Nagai, K., Li, J., Oubridge, C. Description: Recognition of a signal peptide by the signal recognition partic...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Recognition of a signal peptide by the signal recognition particle== | |
| + | <StructureSection load='3kl4' size='340' side='right'caption='[[3kl4]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3kl4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KL4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kl4 OCA], [https://pdbe.org/3kl4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kl4 RCSB], [https://www.ebi.ac.uk/pdbsum/3kl4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kl4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SRP54_SACS2 SRP54_SACS2] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.[HAMAP-Rule:MF_00306] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/3kl4_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kl4 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Saccharolobus solfataricus P2]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Janda CY]] | ||
| + | [[Category: Li J]] | ||
| + | [[Category: Nagai K]] | ||
| + | [[Category: Oubridge C]] | ||
Current revision
Recognition of a signal peptide by the signal recognition particle
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