1y37
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1y37" size="450" color="white" frame="true" align="right" spinBox="true" caption="1y37, resolution 1.50Å" /> '''Structure of Fluoroa...) |
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| - | [[Image:1y37.gif|left|200px]]<br /><applet load="1y37" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1y37, resolution 1.50Å" /> | ||
| - | '''Structure of Fluoroacetate Dehalogenase from Burkholderia sp. FA1'''<br /> | ||
| - | == | + | ==Structure of Fluoroacetate Dehalogenase from Burkholderia sp. FA1== |
| - | + | <StructureSection load='1y37' size='340' side='right'caption='[[1y37]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1y37]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_sp._FA1 Burkholderia sp. FA1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y37 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y37 OCA], [https://pdbe.org/1y37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y37 RCSB], [https://www.ebi.ac.uk/pdbsum/1y37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y37 ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DEHA_BURSP DEHA_BURSP] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1]<ref>PMID:19218394</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y3/1y37_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y37 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Dehalogenase 3D structures|Dehalogenase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Burkholderia sp. FA1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Omi R]] | ||
Current revision
Structure of Fluoroacetate Dehalogenase from Burkholderia sp. FA1
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