1dpl

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(New page: 200px<br /><applet load="1dpl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dpl, resolution 0.83&Aring;" /> '''A-DNA DECAMER GCGTA(...)
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[[Image:1dpl.gif|left|200px]]<br /><applet load="1dpl" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1dpl, resolution 0.83&Aring;" />
 
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'''A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE'''<br />
 
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==Overview==
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==A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE==
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We have determined single crystal structures of an A-DNA decamer and a, B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the, former is the highest reported thus far for any right-handed nucleic acid, duplex and the quality of the diffraction data allowed determination of, the structure with direct methods. The structures reveal unprecedented, details of DNA fine structure and hydration; in particular, we have, reexamined the overall hydration of A- and B-form DNA, the distribution of, water around phosphate groups, and features of the water structure that, may underlie the B to A transition.
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<StructureSection load='1dpl' size='340' side='right'caption='[[1dpl]], [[Resolution|resolution]] 0.83&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1dpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPL FirstGlance]. <br>
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1DPL is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with SPM and MG as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.83&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=T23:2-O-METHYL-3-METHYL-3-DEOXY-ARABINOFURANOSYL-THYMINE-5-PHOSPHATE'>T23</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpl OCA], [https://pdbe.org/1dpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpl RCSB], [https://www.ebi.ac.uk/pdbsum/1dpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpl ProSAT]</span></td></tr>
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X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10699842 10699842]
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</table>
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[[Category: Protein complex]]
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__TOC__
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[[Category: An, H.]]
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</StructureSection>
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[[Category: Cook, P.Dan.]]
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[[Category: Large Structures]]
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[[Category: Egli, M.]]
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[[Category: An H]]
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[[Category: Joachimiak, A.]]
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[[Category: Dan Cook P]]
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[[Category: Maier, M.A.]]
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[[Category: Egli M]]
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[[Category: Manoharan, M.]]
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[[Category: Joachimiak A]]
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[[Category: Miller, R.]]
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[[Category: Maier MA]]
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[[Category: Minasov, G.]]
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[[Category: Manoharan M]]
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[[Category: Sanishvili, R.]]
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[[Category: Miller R]]
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[[Category: Teplova, M.]]
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[[Category: Minasov G]]
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[[Category: Tereshko, V.]]
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[[Category: Sanishvili R]]
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[[Category: Weeks, C.M.]]
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[[Category: Teplova M]]
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[[Category: MG]]
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[[Category: Tereshko V]]
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[[Category: SPM]]
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[[Category: Weeks CM]]
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[[Category: deoxyribonucleic acid]]
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[[Category: modified a-decamer at 0.83 a resolution]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 03:29:14 2007''
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Current revision

A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE

PDB ID 1dpl

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