3kvv
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3kvv is ON HOLD Authors: Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E. Descripti...) |
|||
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Trapping of an oxocarbenium ion intermediate in UP crystals== | |
| + | <StructureSection load='3kvv' size='340' side='right'caption='[[3kvv]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3kvv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KVV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R2B:1,4-ANHYDRO-D-ERYTHRO-PENT-1-ENITOL'>R2B</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=URF:5-FLUOROURACIL'>URF</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kvv OCA], [https://pdbe.org/3kvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kvv RCSB], [https://www.ebi.ac.uk/pdbsum/3kvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kvv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UDP_ECOLI UDP_ECOLI] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/3kvv_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kvv ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Escherichia coli K-12]] | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Begley TP]] | ||
| + | [[Category: Bu W]] | ||
| + | [[Category: Ealick SE]] | ||
| + | [[Category: O'Leary S]] | ||
| + | [[Category: Paul D]] | ||
| + | [[Category: Rajashankar K]] | ||
| + | [[Category: Sanders J]] | ||
| + | [[Category: Settembre E]] | ||
| + | [[Category: Toms A]] | ||
Current revision
Trapping of an oxocarbenium ion intermediate in UP crystals
| |||||||||||
Categories: Escherichia coli K-12 | Large Structures | Begley TP | Bu W | Ealick SE | O'Leary S | Paul D | Rajashankar K | Sanders J | Settembre E | Toms A
