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3hiv

From Proteopedia

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{{Seed}}
 
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[[Image:3hiv.jpg|left|200px]]
 
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==Crystal structure of Saporin-L1 in complex with the trinucleotide inhibitor, a transition state analogue==
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The line below this paragraph, containing "STRUCTURE_3hiv", creates the "Structure Box" on the page.
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<StructureSection load='3hiv' size='340' side='right'caption='[[3hiv]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3hiv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HIV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TXN:(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)-2-({[(S)-({(3R,4R)-4-({[(S)-{[(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-6,8-DIHYDRO-9H-PURIN-9-YL)-2-(HYDROXYMETHYL)-4-METHOXYTETRAHYDROFURAN-3-YL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]PYRROLIDIN-3-YL}OXY)(HYDROXY)PHOSPHORYL]OXY}METHYL)-4-METHOXYTETRAHYDROFURAN-3-YL+3-HYDROXYPROPYL+HYDROGEN+(S)-PHOSPHATE'>TXN</scene></td></tr>
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{{STRUCTURE_3hiv| PDB=3hiv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hiv OCA], [https://pdbe.org/3hiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hiv RCSB], [https://www.ebi.ac.uk/pdbsum/3hiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hiv ProSAT]</span></td></tr>
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</table>
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===Crystal structure of Saporin-L1 in complex with the trinucleotide inhibitor, a transition state analogue===
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== Function ==
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[https://www.uniprot.org/uniprot/Q2QEH4_SAPOF Q2QEH4_SAPOF]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_19920175}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19920175 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3hiv_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19920175}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3HIV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIV OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hiv ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:19920175</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saponaria officinalis]]
[[Category: Saponaria officinalis]]
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[[Category: RRNA N-glycosylase]]
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[[Category: Almo SC]]
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[[Category: Almo, S C.]]
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[[Category: Ho M]]
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[[Category: Ho, M.]]
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[[Category: Schramm VL]]
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[[Category: Schramm, V L.]]
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[[Category: Sturm MB]]
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[[Category: Sturm, M B.]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase/hydrolase inhibitor complex]]
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[[Category: Plant defense]]
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[[Category: Protein synthesis inhibitor]]
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[[Category: Ribosome inactivating protein]]
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[[Category: Rip]]
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[[Category: Toxin]]
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[[Category: Transition state]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:59:00 2009''
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Current revision

Crystal structure of Saporin-L1 in complex with the trinucleotide inhibitor, a transition state analogue

PDB ID 3hiv

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