3jxj

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{{Seed}}
 
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[[Image:3jxj.jpg|left|200px]]
 
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==Crystal structure of the chicken TRPV4 ankyrin repeat domain==
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The line below this paragraph, containing "STRUCTURE_3jxj", creates the "Structure Box" on the page.
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<StructureSection load='3jxj' size='340' side='right'caption='[[3jxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3jxj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JXJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3jxj| PDB=3jxj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jxj OCA], [https://pdbe.org/3jxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jxj RCSB], [https://www.ebi.ac.uk/pdbsum/3jxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jxj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPV4_CHICK TRPV4_CHICK] Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity (PubMed:11081638). Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification (PubMed:11081638). Also activated by phorbol esters (PubMed:19864432). Channel activity seems to be regulated by a calmodulin-dependent mechanism (By similarity).[UniProtKB:Q9HBA0]<ref>PMID:11081638</ref> <ref>PMID:19864432</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/3jxj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jxj ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the chicken TRPV4 ankyrin repeat domain===
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3JXJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JXJ OCA].
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__TOC__
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Choo, S S.]]
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[[Category: Large Structures]]
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[[Category: Gaudet, R.]]
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[[Category: Choo SS]]
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[[Category: Phelps, C B.]]
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[[Category: Gaudet R]]
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[[Category: Ank repeat]]
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[[Category: Phelps CB]]
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[[Category: Ankyrin repeat]]
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[[Category: Ion transport]]
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[[Category: Ionic channel]]
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[[Category: Membrane protein]]
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[[Category: Receptor]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 10:13:43 2009''
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Current revision

Crystal structure of the chicken TRPV4 ankyrin repeat domain

PDB ID 3jxj

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