1v4p

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(New page: 200px<br /><applet load="1v4p" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v4p, resolution 1.45&Aring;" /> '''Crystal structure of...)
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[[Image:1v4p.gif|left|200px]]<br /><applet load="1v4p" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1v4p, resolution 1.45&Aring;" />
 
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'''Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3'''<br />
 
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==About this Structure==
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==Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3==
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1V4P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Alanine--tRNA_ligase Alanine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.7 6.1.1.7] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V4P OCA].
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<StructureSection load='1v4p' size='340' side='right'caption='[[1v4p]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1v4p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V4P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4p OCA], [https://pdbe.org/1v4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v4p RCSB], [https://www.ebi.ac.uk/pdbsum/1v4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v4p ProSAT], [https://www.topsan.org/Proteins/RSGI/1v4p TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALAXS_PYRHO ALAXS_PYRHO] Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala). Has little activity against Gly-tRNA(Ala).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/1v4p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v4p ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Crystal structure of alanyl-tRNA synthetase editing-domain homolog (PH0574) from a hyperthermophile, Pyrococcus horikoshii OT3 at 1.45 A resolution., Ishijima J, Uchida Y, Kuroishi C, Tuzuki C, Takahashi N, Okazaki N, Yutani K, Miyano M, Proteins. 2006 Mar 1;62(4):1133-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16374837 16374837]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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[[Category: Alanine--tRNA ligase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Single protein]]
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[[Category: Ishijima J]]
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[[Category: Ishijima, J.]]
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[[Category: Yutani K]]
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[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
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[[Category: Yutani, K.]]
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[[Category: ZN]]
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[[Category: alanine-trna ligase]]
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[[Category: alanyl-trna synthetase]]
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[[Category: pyrococcus horikoshii]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 04:36:00 2007''
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Current revision

Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3

PDB ID 1v4p

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