This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3kpc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:17, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3kpc.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine==
-
The line below this paragraph, containing "STRUCTURE_3kpc", creates the "Structure Box" on the page.
+
<StructureSection load='3kpc' size='340' side='right'caption='[[3kpc]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3kpc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KPC FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTA:5-DEOXY-5-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-
{{STRUCTURE_3kpc| PDB=3kpc | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kpc OCA], [https://pdbe.org/3kpc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kpc RCSB], [https://www.ebi.ac.uk/pdbsum/3kpc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kpc ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/ASST_METJA ASST_METJA] Required for O-acetylhomoserine sulfhydrylase (OAHS)-independent homocysteine (Hcy) biosynthesis. Together with MJ0099, catalyzes the condensation of sulfide with aspartate semialdehyde to generate homocysteine. Likely functions through persulfide intermediate.[UniProtKB:Q8TPT4]
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
3KPC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KPC OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/3kpc_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kpc ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
-
[[Category: Arribas, E Astigarraga.]]
+
[[Category: Arribas EA]]
-
[[Category: Encinar, J A.]]
+
[[Category: Encinar JA]]
-
[[Category: Fernandez, J A.]]
+
[[Category: Fernandez JA]]
-
[[Category: Garcia, I Gomez.]]
+
[[Category: Garcia IG]]
-
[[Category: Kortazar, D.]]
+
[[Category: Kortazar D]]
-
[[Category: Lucas, M.]]
+
[[Category: Lucas M]]
-
[[Category: Martinez-Chantar, M L.]]
+
[[Category: Martinez-Chantar ML]]
-
[[Category: Martinez-Cruz, L A.]]
+
[[Category: Martinez-Cruz LA]]
-
[[Category: Mato, J M.]]
+
[[Category: Mato JM]]
-
[[Category: Oyenarte, I.]]
+
[[Category: Oyenarte I]]
-
[[Category: Cbs domain]]
+
-
[[Category: Conformational change]]
+
-
[[Category: S-adenosylmethionine]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:40:59 2010''
+

Current revision

Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine

PDB ID 3kpc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools