2gow

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{{Seed}}
 
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[[Image:2gow.png|left|200px]]
 
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==Solution structure of BC059385 from Homo sapiens==
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The line below this paragraph, containing "STRUCTURE_2gow", creates the "Structure Box" on the page.
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<StructureSection load='2gow' size='340' side='right'caption='[[2gow]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2gow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GOW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gow OCA], [https://pdbe.org/2gow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gow RCSB], [https://www.ebi.ac.uk/pdbsum/2gow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gow ProSAT], [https://www.topsan.org/Proteins/CESG/2gow TOPSAN]</span></td></tr>
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{{STRUCTURE_2gow| PDB=2gow | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UBL3_HUMAN UBL3_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2gow_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gow ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The protein Bc059385, whose solution structure is reported here, is the human representative of a recently identified family of membrane-anchored ubiquitin-fold (MUB) proteins. Analysis of their similarity to ubiquitin indicates that homologous amino acid residues in MUBs form a hydrophobic surface very similar to the recognition patch surrounding Ile-44 in ubiquitin. This suggests that MUBs may interact with proteins containing an alpha-helical motif similar to those of some ubiquitin binding domains. A disordered loop common to MUBs may also provide a second protein interaction site. From the available data, it is probable that this protein is prenylated and associated with the membrane. With &lt;20% identity to ubiquitin, the MUB family further expands the sequence space that maps to the beta-grasp fold, and adds membrane localization to its list of functional roles.
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===Solution structure of BC059385 from Homo sapiens===
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Solution structure of a membrane-anchored ubiquitin-fold (MUB) protein from Homo sapiens.,de la Cruz NB, Peterson FC, Lytle BL, Volkman BF Protein Sci. 2007 Jul;16(7):1479-84. Epub 2007 Jun 13. PMID:17567738<ref>PMID:17567738</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_17567738}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2gow" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 17567738 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_17567738}}
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__TOC__
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</StructureSection>
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==About this Structure==
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2GOW is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOW OCA].
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==Reference==
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<ref group="xtra">PMID:17567738</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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[[Category: Large Structures]]
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[[Category: Cruz, N B.de la.]]
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[[Category: Lytle BL]]
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[[Category: Lytle, B L.]]
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[[Category: Peterson FC]]
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[[Category: Peterson, F C.]]
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[[Category: Volkman BF]]
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[[Category: Volkman, B F.]]
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[[Category: De la Cruz NB]]
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[[Category: Bc059385]]
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[[Category: Center for eukaryotic structural genomic]]
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[[Category: Cesg]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 10:31:28 2010''
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Current revision

Solution structure of BC059385 from Homo sapiens

PDB ID 2gow

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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