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2kin

From Proteopedia

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{{Seed}}
 
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[[Image:2kin.png|left|200px]]
 
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<!--
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==KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS==
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The line below this paragraph, containing "STRUCTURE_2kin", creates the "Structure Box" on the page.
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<StructureSection load='2kin' size='340' side='right'caption='[[2kin]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2kin]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The April 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KIN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2kin| PDB=2kin | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kin OCA], [https://pdbe.org/2kin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kin RCSB], [https://www.ebi.ac.uk/pdbsum/2kin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kin ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KIF5C_RAT KIF5C_RAT] Microtubule-associated force-producing protein that may play a role in organelle transport (By similarity). Has ATPase activity (PubMed:27452403). Involved in synaptic transmission (By similarity). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (PubMed:23576431).[UniProtKB:O60282][UniProtKB:P28738]<ref>PMID:23576431</ref> <ref>PMID:27452403</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ki/2kin_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kin ConSurf].
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<div style="clear:both"></div>
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===KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS===
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==See Also==
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*[[Kinesin 3D Structures|Kinesin 3D Structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_9405049}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 9405049 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_9405049}}
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==About this Structure==
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2KIN is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The April 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIN OCA].
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==Reference==
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<ref group="xtra">PMID:9405049</ref><references group="xtra"/>
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[[Category: Kinesin]]
[[Category: Kinesin]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Biou, V.]]
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[[Category: Biou V]]
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[[Category: Brady, S T.]]
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[[Category: Brady ST]]
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[[Category: Kozielski, F.]]
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[[Category: Kozielski F]]
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[[Category: Mandelkow, E.]]
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[[Category: Mandelkow E]]
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[[Category: Mandelkow, E M.]]
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[[Category: Mandelkow E-M]]
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[[Category: Marx, A.]]
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[[Category: Marx A]]
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[[Category: Muller, J.]]
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[[Category: Muller J]]
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[[Category: Sack, S.]]
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[[Category: Sack S]]
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[[Category: Thormahlen, M.]]
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[[Category: Thormahlen M]]
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[[Category: Cytoskeleton]]
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[[Category: Motor protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:33:31 2010''
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Current revision

KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS

PDB ID 2kin

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