2x34
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2x34 is ON HOLD until Paper Publication Authors: Vincent, F., Dal Molin, D., Weiner, R.M., Bourne, Y., Henrissat, B. Description: Structure of a po...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown== | |
| + | <StructureSection load='2x34' size='340' side='right'caption='[[2x34]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2x34]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharophagus_degradans_2-40 Saccharophagus degradans 2-40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X34 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UQ8:UBIQUINONE-8'>UQ8</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x34 OCA], [https://pdbe.org/2x34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x34 RCSB], [https://www.ebi.ac.uk/pdbsum/2x34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x34 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q21LI5_SACD2 Q21LI5_SACD2] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x3/2x34_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x34 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Saccharophagus degradans belongs to a recently discovered group of marine bacteria equipped with an arsenal of sugar cleaving enzymes coupled to carbohydrate-binding domains to degrade various insoluble complex polysaccharides. The modular Sde-1182 protein consists of a family 2 carbohydrate binding module linked to a X158 domain of unknown function. The 1.9 A and 1.55 A resolution crystal structures of the isolated X158 domain bound to the two related polyisoprenoid molecules, ubiquinone and octaprenyl pyrophosphate, unveil a beta-barrel architecture reminiscent of the YceI-like superfamily that resembles the architecture of the lipocalin fold. This unprecedented association coupling oxidoreduction and carbohydrate recognition events may have implications for effective nutrient uptake in the marine environment. | ||
| - | + | Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown.,Vincent F, Molin DD, Weiner RM, Bourne Y, Henrissat B FEBS Lett. 2010 Apr 16;584(8):1577-84. Epub 2010 Mar 16. PMID:20227408<ref>PMID:20227408</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2x34" style="background-color:#fffaf0;"></div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharophagus degradans 2-40]] | ||
| + | [[Category: Bourne Y]] | ||
| + | [[Category: Dal Molin D]] | ||
| + | [[Category: Henrissat B]] | ||
| + | [[Category: Vincent F]] | ||
| + | [[Category: Weiner RM]] | ||
Current revision
Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown
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