3fwr

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{{Seed}}
 
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[[Image:3fwr.jpg|left|200px]]
 
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==Crystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor complexed with ADP==
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The line below this paragraph, containing "STRUCTURE_3fwr", creates the "Structure Box" on the page.
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<StructureSection load='3fwr' size='340' side='right'caption='[[3fwr]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fwr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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{{STRUCTURE_3fwr| PDB=3fwr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwr OCA], [https://pdbe.org/3fwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwr RCSB], [https://www.ebi.ac.uk/pdbsum/3fwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwr ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor complexed with ADP===
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== Function ==
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[https://www.uniprot.org/uniprot/CCPN_BACSU CCPN_BACSU] Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes.<ref>PMID:15720552</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3FWR is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWR OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwr ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Arold, S.]]
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[[Category: Large Structures]]
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[[Category: Chaix, D.]]
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[[Category: Arold S]]
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[[Category: Declerck, N.]]
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[[Category: Chaix D]]
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[[Category: Hoh, F.]]
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[[Category: Declerck N]]
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[[Category: Cbs domain dimer]]
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[[Category: Hoh F]]
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[[Category: Central glycolytic gene regulator]]
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[[Category: Metabolism regulator]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:58:00 2010''
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Current revision

Crystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor complexed with ADP

PDB ID 3fwr

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