3kpt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:05, 6 November 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3kpt.png|left|200px]]
 
-
<!--
+
==Crystal structure of BcpA, the major pilin subunit of Bacillus cereus==
-
The line below this paragraph, containing "STRUCTURE_3kpt", creates the "Structure Box" on the page.
+
<StructureSection load='3kpt' size='340' side='right'caption='[[3kpt]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3kpt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_ATCC_14579 Bacillus cereus ATCC 14579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KPT FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.102&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_3kpt| PDB=3kpt | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kpt OCA], [https://pdbe.org/3kpt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kpt RCSB], [https://www.ebi.ac.uk/pdbsum/3kpt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kpt ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q81D71_BACCR Q81D71_BACCR]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/3kpt_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kpt ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Gram-positive bacteria elaborate pili and do so without the participation of folding chaperones or disulfide bond catalysts. Sortases, enzymes that cut pilin precursors, form covalent bonds that link pilin subunits and assemble pili on the bacterial surface. We determined the x-ray structure of BcpA, the major pilin subunit of Bacillus cereus. The BcpA precursor encompasses 2 Ig folds (CNA(2) and CNA(3)) and one jelly-roll domain (XNA) each of which synthesizes a single intramolecular amide bond. A fourth amide bond, derived from the Ig fold of CNA(1), is formed only after pilin subunits have been incorporated into pili. We report that the domains of pilin precursors have evolved to synthesize a discrete sequence of intramolecular amide bonds, thereby conferring structural stability and protease resistance to pili.
-
===Crystal structure of BcpA, the major pilin subunit of Bacillus cereus===
+
Intramolecular amide bonds stabilize pili on the surface of bacilli.,Budzik JM, Poor CB, Faull KF, Whitelegge JP, He C, Schneewind O Proc Natl Acad Sci U S A. 2009 Nov 10. PMID:19903875<ref>PMID:19903875</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3kpt" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_19903875}}, adds the Publication Abstract to the page
+
*[[Pilin 3D structures|Pilin 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 19903875 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_19903875}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Bacillus cereus ATCC 14579]]
-
3KPT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacillus_cereus_atcc_14579 Bacillus cereus atcc 14579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KPT OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Budzik JM]]
-
==Reference==
+
[[Category: He C]]
-
<ref group="xtra">PMID:19903875</ref><references group="xtra"/>
+
[[Category: Poor CB]]
-
[[Category: Bacillus cereus atcc 14579]]
+
[[Category: Schneewind O]]
-
[[Category: Budzik, J M.]]
+
-
[[Category: He, C.]]
+
-
[[Category: Poor, C B.]]
+
-
[[Category: Schneewind, O.]]
+
-
[[Category: Beta sheet]]
+
-
[[Category: Intramolecular amide bond]]
+
-
[[Category: Pilin subunit]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:23:38 2010''
+

Current revision

Crystal structure of BcpA, the major pilin subunit of Bacillus cereus

PDB ID 3kpt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3kpt"
Personal tools