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3hf6

From Proteopedia

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{{Seed}}
 
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[[Image:3hf6.png|left|200px]]
 
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==Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE==
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The line below this paragraph, containing "STRUCTURE_3hf6", creates the "Structure Box" on the page.
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<StructureSection load='3hf6' size='340' side='right'caption='[[3hf6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3hf6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HF6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=LX0:4-(4-AMINO-6-{[(1R)-1-NAPHTHALEN-2-YLETHYL]AMINO}-1,3,5-TRIAZIN-2-YL)-L-PHENYLALANINE'>LX0</scene></td></tr>
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{{STRUCTURE_3hf6| PDB=3hf6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hf6 OCA], [https://pdbe.org/3hf6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hf6 RCSB], [https://www.ebi.ac.uk/pdbsum/3hf6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hf6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPH1_HUMAN TPH1_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/3hf6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hf6 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE===
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==See Also==
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*[[Hydroxylases 3D structures|Hydroxylases 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_19631532}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19631532 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19631532}}
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==About this Structure==
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3HF6 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HF6 OCA].
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==Reference==
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<ref group="xtra">PMID:19631532</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Tryptophan 5-monooxygenase]]
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[[Category: Large Structures]]
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[[Category: Hunter, M J.]]
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[[Category: Hunter MJ]]
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[[Category: Swanson, R V.]]
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[[Category: Swanson RV]]
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[[Category: Tari, L W.]]
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[[Category: Tari LW]]
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[[Category: Alternative splicing]]
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[[Category: Iron]]
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[[Category: Metal-binding]]
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[[Category: Monooxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: Phosphoprotein]]
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[[Category: Serotonin biosynthesis]]
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[[Category: Tryptophan 5-hydroxylase 1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:42:49 2010''
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Current revision

Crystal structure of human tryptophan hydroxylase type 1 with bound LP-521834 and FE

PDB ID 3hf6

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