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3h6q

From Proteopedia

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{{Seed}}
 
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[[Image:3h6q.png|left|200px]]
 
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<!--
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==Macrocypin, a beta-trefoil cysteine protease inhibitor==
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The line below this paragraph, containing "STRUCTURE_3h6q", creates the "Structure Box" on the page.
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<StructureSection load='3h6q' size='340' side='right'caption='[[3h6q]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3h6q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Macrolepiota_procera Macrolepiota procera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H6Q FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.643&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h6q OCA], [https://pdbe.org/3h6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h6q RCSB], [https://www.ebi.ac.uk/pdbsum/3h6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h6q ProSAT]</span></td></tr>
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{{STRUCTURE_3h6q| PDB=3h6q | SCENE= }}
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</table>
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== Function ==
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===Macrocypin, a Kunitz type cysteine protease inhibitor===
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[https://www.uniprot.org/uniprot/MCP1A_MACPC MCP1A_MACPC] Inhibits papain and cysteine cathepsin endopeptidases, and also inhibits cathepsins B and H, which exhibit both exopeptidase and endopeptidase activities.<ref>PMID:19678836</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_19846555}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 19846555 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/3h6q_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_19846555}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h6q ConSurf].
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3H6Q is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Macrolepiota_procera Macrolepiota procera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6Q OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:19846555</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Macrolepiota procera]]
[[Category: Macrolepiota procera]]
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[[Category: Brzin, J.]]
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[[Category: Brzin J]]
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[[Category: Renko, M.]]
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[[Category: Renko M]]
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[[Category: Sabotic, J.]]
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[[Category: Sabotic J]]
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[[Category: Turk, D.]]
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[[Category: Turk D]]
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[[Category: Beta trefoil]]
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[[Category: Cysteine protease inhibitor]]
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[[Category: Hydrolase/hydrolase inhibitor complex]]
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[[Category: Kunitz type inhibitor]]
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[[Category: Macrocypin]]
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[[Category: Mycocypin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 15:13:36 2010''
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Current revision

Macrocypin, a beta-trefoil cysteine protease inhibitor

PDB ID 3h6q

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