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3iba

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{{Seed}}
 
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[[Image:3iba.jpg|left|200px]]
 
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==Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+==
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The line below this paragraph, containing "STRUCTURE_3iba", creates the "Structure Box" on the page.
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<StructureSection load='3iba' size='340' side='right'caption='[[3iba]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3iba]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IBA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr>
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{{STRUCTURE_3iba| PDB=3iba | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iba OCA], [https://pdbe.org/3iba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iba RCSB], [https://www.ebi.ac.uk/pdbsum/3iba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iba ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q95WL3_TRYCR Q95WL3_TRYCR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ib/3iba_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iba ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+===
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==See Also==
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_19876942}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 19876942 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19876942}}
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==About this Structure==
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3IBA is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBA OCA].
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==Reference==
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<ref group="xtra">PMID:19876942</ref><references group="xtra"/>
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[[Category: Geranyltranstransferase]]
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[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Amzel, L M.]]
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[[Category: Amzel LM]]
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[[Category: Gabelli, S B.]]
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[[Category: Gabelli SB]]
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[[Category: Huang, C H.]]
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[[Category: Huang CH]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Bisphosphonate]]
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[[Category: Chagas disease]]
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[[Category: Fpp]]
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[[Category: Isopentenyl pyrophosphate]]
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[[Category: Isoprene biosynthesis]]
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[[Category: Transferase]]
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[[Category: Trypanosoma cruzi]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 17:29:08 2010''
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Current revision

Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+

PDB ID 3iba

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