2pnv

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{{Seed}}
 
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[[Image:2pnv.png|left|200px]]
 
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==Crystal Structure of the leucine zipper domain of small-conductance Ca2+-activated K+ (SKCa) channel from Rattus norvegicus==
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The line below this paragraph, containing "STRUCTURE_2pnv", creates the "Structure Box" on the page.
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<StructureSection load='2pnv' size='340' side='right'caption='[[2pnv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PNV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pnv OCA], [https://pdbe.org/2pnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pnv RCSB], [https://www.ebi.ac.uk/pdbsum/2pnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pnv ProSAT]</span></td></tr>
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{{STRUCTURE_2pnv| PDB=2pnv | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KCNN2_RAT KCNN2_RAT] Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pnv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pnv ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the leucine zipper domain of small-conductance Ca2+-activated K+ (SKCa) channel from Rattus norvegicus===
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==See Also==
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*[[Potassium channel 3D structures|Potassium channel 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2PNV is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNV OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:17910055</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Eom, S H.]]
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[[Category: Eom SH]]
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[[Category: Kang, G B.]]
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[[Category: Kang GB]]
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[[Category: Kim, J Y.]]
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[[Category: Kim JY]]
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[[Category: Kim, M K.]]
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[[Category: Kim MK]]
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[[Category: Park, C S.]]
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[[Category: Park CS]]
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[[Category: Leucine zipper]]
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[[Category: Membrane protein]]
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[[Category: Rattus norvegicus]]
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[[Category: Skca channel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 09:52:06 2010''
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Current revision

Crystal Structure of the leucine zipper domain of small-conductance Ca2+-activated K+ (SKCa) channel from Rattus norvegicus

PDB ID 2pnv

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