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3i4o

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{{Seed}}
 
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[[Image:3i4o.jpg|left|200px]]
 
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<!--
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==Crystal Structure of Translation Initiation Factor 1 from Mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_3i4o", creates the "Structure Box" on the page.
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<StructureSection load='3i4o' size='340' side='right'caption='[[3i4o]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3i4o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I4O FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i4o OCA], [https://pdbe.org/3i4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i4o RCSB], [https://www.ebi.ac.uk/pdbsum/3i4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i4o ProSAT]</span></td></tr>
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{{STRUCTURE_3i4o| PDB=3i4o | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Translation Initiation Factor 1 from Mycobacterium tuberculosis===
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[https://www.uniprot.org/uniprot/IF1_MYCTU IF1_MYCTU] No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_20132820}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 20132820 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i4/3i4o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_20132820}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i4o ConSurf].
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3I4O is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I4O OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:20132820</ref><ref group="xtra">PMID:17329809</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Hatzopoulos, G N.]]
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[[Category: Hatzopoulos GN]]
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[[Category: Mueller-Dieckmann, J.]]
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[[Category: Mueller-Dieckmann J]]
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[[Category: Cytoplasm]]
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[[Category: If1]]
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[[Category: Initiation factor]]
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[[Category: Protein biosynthesis]]
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[[Category: Translation]]
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[[Category: Translation initiation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:43:30 2010''
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Current revision

Crystal Structure of Translation Initiation Factor 1 from Mycobacterium tuberculosis

PDB ID 3i4o

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