3acg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:18, 1 November 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3acg.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of Carbohydrate-Binding Module Family 28 from Clostridium josui Cel5A in complex with cellobiose==
-
The line below this paragraph, containing "STRUCTURE_3acg", creates the "Structure Box" on the page.
+
<StructureSection load='3acg' size='340' side='right'caption='[[3acg]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3acg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruminiclostridium_josui Ruminiclostridium josui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ACG FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PRD_900005:beta-cellobiose'>PRD_900005</scene></td></tr>
-
{{STRUCTURE_3acg| PDB=3acg | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3acg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acg OCA], [https://pdbe.org/3acg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3acg RCSB], [https://www.ebi.ac.uk/pdbsum/3acg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3acg ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q59290_RUMJO Q59290_RUMJO]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ac/3acg_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3acg ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The crystal structures of a carbohydrate-binding module (CBM) family 28 domain of endoglucanase Cel5A from Clostridium josui have been determined in ligand-free and complex forms with cellobiose, cellotetraose, and cellopentaose as the first complex structures of this family. In the cleft of a beta-sandwich fold, the ligands are recognized by stacking interactions and hydrogen bonds. Conformations of the bound cellooligosaccharides are similar to those in crystals and solution but clearly different from the cellulose structure. Interestingly, the glucan chain bound on CBM28 is in the opposite direction of that bound to CBM17, although these families share significant structural similarity.
-
===Crystal Structure of Carbohydrate-Binding Module Family 28 from Clostridium josui Cel5A in complex with cellobiose===
+
Recognition of cellooligosaccharides by a family 28 carbohydrate-binding module.,Tsukimoto K, Takada R, Araki Y, Suzuki K, Karita S, Wakagi T, Shoun H, Watanabe T, Fushinobu S FEBS Lett. 2010 Mar 19;584(6):1205-11. Epub 2010 Feb 14. PMID:20159017<ref>PMID:20159017</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3acg" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_20159017}}, adds the Publication Abstract to the page
+
*[[Glucanase 3D structures|Glucanase 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 20159017 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_20159017}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
3ACG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_josui Clostridium josui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACG OCA].
+
[[Category: Ruminiclostridium josui]]
-
 
+
[[Category: Araki Y]]
-
==Reference==
+
[[Category: Fushinobu S]]
-
<ref group="xtra">PMID:20159017</ref><references group="xtra"/>
+
[[Category: Karita S]]
-
[[Category: Cellulase]]
+
[[Category: Shoun H]]
-
[[Category: Clostridium josui]]
+
[[Category: Suzuki K]]
-
[[Category: Araki, Y.]]
+
[[Category: Takada R]]
-
[[Category: Fushinobu, S.]]
+
[[Category: Tsukimoto K]]
-
[[Category: Karita, S.]]
+
[[Category: Wakagi T]]
-
[[Category: Shoun, H.]]
+
[[Category: Watanabe T]]
-
[[Category: Suzuki, K.]]
+
-
[[Category: Takada, R.]]
+
-
[[Category: Tsukimoto, K.]]
+
-
[[Category: Wakagi, T.]]
+
-
[[Category: Watanabe, T.]]
+
-
[[Category: Beta-jellyroll]]
+
-
[[Category: Cellulose-binding domain]]
+
-
[[Category: Hydrolase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:38:03 2010''
+

Current revision

Crystal Structure of Carbohydrate-Binding Module Family 28 from Clostridium josui Cel5A in complex with cellobiose

PDB ID 3acg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3acg"
Personal tools