2ksg

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{{Seed}}
 
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[[Image:2ksg.jpg|left|200px]]
 
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==Solution structure of dermcidin-1L, a human antibiotic peptide==
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The line below this paragraph, containing "STRUCTURE_2ksg", creates the "Structure Box" on the page.
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<StructureSection load='2ksg' size='340' side='right'caption='[[2ksg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ksg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KSG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ksg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksg OCA], [https://pdbe.org/2ksg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ksg RCSB], [https://www.ebi.ac.uk/pdbsum/2ksg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ksg ProSAT]</span></td></tr>
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{{STRUCTURE_2ksg| PDB=2ksg | SCENE= }}
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</table>
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== Function ==
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===Solution structure of dermcidin-1L, a human antibiotic peptide===
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[https://www.uniprot.org/uniprot/DCD_HUMAN DCD_HUMAN] DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.<ref>PMID:17448443</ref> Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.<ref>PMID:17448443</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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2KSG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSG OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Jung, H.]]
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[[Category: Large Structures]]
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[[Category: Kim, J.]]
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[[Category: Jung H]]
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[[Category: Yang, S.]]
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[[Category: Kim J]]
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[[Category: Amphipathic alpha helix]]
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[[Category: Yang S]]
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[[Category: Antibiotic]]
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[[Category: Antibiotic peptide]]
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[[Category: Peptide-membrane interaction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:50:57 2010''
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Current revision

Solution structure of dermcidin-1L, a human antibiotic peptide

PDB ID 2ksg

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