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3lxy

From Proteopedia

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(New page: {{Seed}} 200px <!-- The line below this paragraph, containing "STRUCTURE_3lxy", creates the "Structure Box" on the page. You may change the PDB parameter (which se...)
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[[Image:3lxy.jpg|left|200px]]
 
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==Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92==
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The line below this paragraph, containing "STRUCTURE_3lxy", creates the "Structure Box" on the page.
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<StructureSection load='3lxy' size='340' side='right'caption='[[3lxy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LXY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3lxy| PDB=3lxy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lxy OCA], [https://pdbe.org/3lxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lxy RCSB], [https://www.ebi.ac.uk/pdbsum/3lxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lxy ProSAT]</span></td></tr>
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</table>
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===Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92===
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== Function ==
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[https://www.uniprot.org/uniprot/PDXA_YERPE PDXA_YERPE] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity).
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3LXY is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LXY OCA].
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Check<jmol>
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[[Category: 4-hydroxythreonine-4-phosphate dehydrogenase]]
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lx/3lxy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lxy ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Yersinia pestis]]
[[Category: Yersinia pestis]]
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[[Category: Anderson, W.]]
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[[Category: Anderson W]]
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[[Category: Diseases, Center for Structural Genomics of Infectious.]]
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[[Category: Joachimiak, A.]]
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[[Category: Kwon, K.]]
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[[Category: Maltseva, N.]]
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[[Category: Nocek, B.]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: Dehydrogenase]]
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[[Category: Metal-binding]]
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[[Category: Nad]]
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[[Category: Nad-dependent]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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[[Category: Pdxa]]
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[[Category: Pyridoxine biosynthesis]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 14:56:34 2010''
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[[Category: Kwon K]]
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[[Category: Maltseva N]]
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[[Category: Nocek B]]

Current revision

Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92

PDB ID 3lxy

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