This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2rq9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (19:15, 29 May 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2rq9.jpg|left|200px]]
 
-
<!--
+
==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new==
-
The line below this paragraph, containing "STRUCTURE_2rq9", creates the "Structure Box" on the page.
+
<StructureSection load='2rq9' size='340' side='right'caption='[[2rq9]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQ9 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rq9 OCA], [https://pdbe.org/2rq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rq9 ProSAT]</span></td></tr>
-
{{STRUCTURE_2rq9| PDB=2rq9 | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rq9_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rq9 ConSurf].
 +
<div style="clear:both"></div>
-
===Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new===
+
==See Also==
-
 
+
*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
2RQ9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Enomoto, M.]]
+
[[Category: Large Structures]]
-
[[Category: Hosoda, K.]]
+
[[Category: Enomoto M]]
-
[[Category: Inoue, Y.]]
+
[[Category: Hosoda K]]
-
[[Category: Ishii, T.]]
+
[[Category: Inoue Y]]
-
[[Category: Nameki, N.]]
+
[[Category: Ishii T]]
-
[[Category: Tochio, N.]]
+
[[Category: Nameki N]]
-
[[Category: Wakamatsu, K.]]
+
[[Category: Tochio N]]
-
[[Category: Xiang, L.]]
+
[[Category: Wakamatsu K]]
-
[[Category: Acetylation]]
+
[[Category: Xiang L]]
-
[[Category: Alternative splicing]]
+
-
[[Category: Angiogenesis]]
+
-
[[Category: Beta-trefoil]]
+
-
[[Category: Developmental protein]]
+
-
[[Category: Differentiation]]
+
-
[[Category: Growth factor]]
+
-
[[Category: Heparin-binding]]
+
-
[[Category: Mitogen]]
+
-
[[Category: Polymorphism]]
+
-
[[Category: Protein binding]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:36:29 2010''
+

Current revision

Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new

PDB ID 2rq9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools