2rq9

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{{Seed}}
 
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[[Image:2rq9.jpg|left|200px]]
 
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==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new==
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The line below this paragraph, containing "STRUCTURE_2rq9", creates the "Structure Box" on the page.
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<StructureSection load='2rq9' size='340' side='right'caption='[[2rq9]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQ9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rq9 OCA], [https://pdbe.org/2rq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rq9 ProSAT]</span></td></tr>
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{{STRUCTURE_2rq9| PDB=2rq9 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rq9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rq9 ConSurf].
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<div style="clear:both"></div>
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===Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new===
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==See Also==
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*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2RQ9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Enomoto, M.]]
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[[Category: Large Structures]]
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[[Category: Hosoda, K.]]
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[[Category: Enomoto M]]
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[[Category: Inoue, Y.]]
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[[Category: Hosoda K]]
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[[Category: Ishii, T.]]
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[[Category: Inoue Y]]
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[[Category: Nameki, N.]]
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[[Category: Ishii T]]
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[[Category: Tochio, N.]]
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[[Category: Nameki N]]
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[[Category: Wakamatsu, K.]]
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[[Category: Tochio N]]
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[[Category: Xiang, L.]]
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[[Category: Wakamatsu K]]
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[[Category: Acetylation]]
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[[Category: Xiang L]]
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[[Category: Alternative splicing]]
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[[Category: Angiogenesis]]
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[[Category: Beta-trefoil]]
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[[Category: Developmental protein]]
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[[Category: Differentiation]]
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[[Category: Growth factor]]
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[[Category: Heparin-binding]]
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[[Category: Mitogen]]
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[[Category: Polymorphism]]
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[[Category: Protein binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:36:29 2010''
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Current revision

Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new

PDB ID 2rq9

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