2wz9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:20, 20 December 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2wz9.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of the thioredoxin domain of human TXNL2==
-
The line below this paragraph, containing "STRUCTURE_2wz9", creates the "Structure Box" on the page.
+
<StructureSection load='2wz9' size='340' side='right'caption='[[2wz9]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2wz9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WZ9 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wz9 OCA], [https://pdbe.org/2wz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wz9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wz9 ProSAT]</span></td></tr>
-
{{STRUCTURE_2wz9| PDB=2wz9 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===CRYSTAL STRUCTURE OF THE THIOREDOXIN DOMAIN OF HUMAN TXNL2===
+
[https://www.uniprot.org/uniprot/GLRX3_HUMAN GLRX3_HUMAN] Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
2WZ9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WZ9 OCA].
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wz/2wz9_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wz9 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bountra, C.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Cocking, R.]]
+
[[Category: Bountra C]]
-
[[Category: Delft, F Von.]]
+
[[Category: Cocking R]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Johannson, C.]]
+
[[Category: Johannson C]]
-
[[Category: Kavanagh, K L.]]
+
[[Category: Kavanagh KL]]
-
[[Category: Muniz, J R.C.]]
+
[[Category: Muniz JRC]]
-
[[Category: Pike, A C.W.]]
+
[[Category: Pike ACW]]
-
[[Category: Vollmar, M.]]
+
[[Category: Vollmar M]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Protein binding]]
+
[[Category: Von Delft F]]
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:37:06 2010''
+

Current revision

Crystal structure of the thioredoxin domain of human TXNL2

PDB ID 2wz9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools