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3lm0

From Proteopedia

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{{Seed}}
 
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[[Image:3lm0.jpg|left|200px]]
 
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<!--
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==Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)==
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The line below this paragraph, containing "STRUCTURE_3lm0", creates the "Structure Box" on the page.
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<StructureSection load='3lm0' size='340' side='right'caption='[[3lm0]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LM0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EBD:[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]-5-METHYLPYRIMIDIN-2-YL}AMINO)PHENYL]ACETONITRILE'>EBD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_3lm0| PDB=3lm0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lm0 OCA], [https://pdbe.org/3lm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lm0 RCSB], [https://www.ebi.ac.uk/pdbsum/3lm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lm0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lm/3lm0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lm0 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)===
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==See Also==
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3LM0 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM0 OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Bountra C]]
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[[Category: Chaikuad, A.]]
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[[Category: Chaikuad A]]
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[[Category: Delft, F von.]]
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[[Category: Edwards A]]
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[[Category: Edwards, A.]]
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[[Category: Fedorov O]]
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[[Category: Fedorov, O.]]
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[[Category: Filippakopoulos P]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Hapka E]]
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[[Category: Hapka, E.]]
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[[Category: Knapp S]]
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[[Category: Knapp, S.]]
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[[Category: Phillips C]]
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[[Category: Phillips, C.]]
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[[Category: Pike ACW]]
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[[Category: Pike, A C.W.]]
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[[Category: Rellos P]]
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[[Category: Rellos, P.]]
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[[Category: Soundararajan M]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Ugochukwu E]]
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[[Category: Soundararajan, M.]]
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[[Category: Wang J]]
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[[Category: Ugochukwu, E.]]
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[[Category: Weigelt J]]
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[[Category: Wang, J.]]
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[[Category: Von Delft F]]
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[[Category: Weigelt, J.]]
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[[Category: Apoptosis]]
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[[Category: Atp-binding]]
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[[Category: Dap kinase related apoptosis-inducing protein kinase 2]]
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[[Category: Death-associated protein kinase-related 2]]
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[[Category: Drak2]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Serine/threonine kinase 17b]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Sgc]]
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[[Category: Stk17b]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:44:38 2010''
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Current revision

Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)

PDB ID 3lm0

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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