2kvg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2kvg is ON HOLD Authors: Chou, C., Lou, Y., Chen, C. Description: Structure of the three-Cys2His2 domain of mouse testis zinc finger protein ''Pag...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the three-Cys2His2 domain of mouse testis zinc finger protein== | |
| - | + | <StructureSection load='2kvg' size='340' side='right'caption='[[2kvg]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2kvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KVG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | '' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kvg OCA], [https://pdbe.org/2kvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kvg RCSB], [https://www.ebi.ac.uk/pdbsum/2kvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kvg ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZBT32_MOUSE ZBT32_MOUSE] DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.<ref>PMID:11279021</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Chen C]] | ||
| + | [[Category: Chou C-C]] | ||
| + | [[Category: Lou Y-C]] | ||
Current revision
Structure of the three-Cys2His2 domain of mouse testis zinc finger protein
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