3k6t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:15, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3k6t.png|left|200px]]
 
-
<!--
+
==Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution==
-
The line below this paragraph, containing "STRUCTURE_3k6t", creates the "Structure Box" on the page.
+
<StructureSection load='3k6t' size='340' side='right'caption='[[3k6t]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3k6t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K6T FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6t OCA], [https://pdbe.org/3k6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k6t RCSB], [https://www.ebi.ac.uk/pdbsum/3k6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k6t ProSAT]</span></td></tr>
-
{{STRUCTURE_3k6t| PDB=3k6t | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution===
+
[https://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_20223220}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 20223220 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/3k6t_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_20223220}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k6t ConSurf].
-
3K6T is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6T OCA].
+
<div style="clear:both"></div>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:20223220</ref><references group="xtra"/>
+
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
-
[[Category: Beuck, C.]]
+
[[Category: Large Structures]]
-
[[Category: Carmel, A B.]]
+
[[Category: Beuck C]]
-
[[Category: Columbus, L.]]
+
[[Category: Carmel AB]]
-
[[Category: Kerkow, D E.]]
+
[[Category: Columbus L]]
-
[[Category: Stanfield, R L.]]
+
[[Category: Kerkow DE]]
-
[[Category: Szymczyna, B R.]]
+
[[Category: Stanfield RL]]
-
[[Category: Williamson, J R.]]
+
[[Category: Szymczyna BR]]
-
[[Category: Developmental protein]]
+
[[Category: Williamson JR]]
-
[[Category: Differentiation]]
+
-
[[Category: Gld-1]]
+
-
[[Category: Helix-turn-helix motif]]
+
-
[[Category: Hydrophobic homodimer interface]]
+
-
[[Category: Meiosis]]
+
-
[[Category: Oogenesis]]
+
-
[[Category: Perpendicular stacking of protomer]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Qua1 homodimerization domain]]
+
-
[[Category: Rna-binding]]
+
-
[[Category: Translation regulation]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 12:56:49 2010''
+

Current revision

Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution

PDB ID 3k6t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3k6t"
Personal tools