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3guu

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{{Seed}}
 
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[[Image:3guu.jpg|left|200px]]
 
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==X-ray structure of Candida Antarctica lipase A==
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The line below this paragraph, containing "STRUCTURE_3guu", creates the "Structure Box" on the page.
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<StructureSection load='3guu' size='340' side='right'caption='[[3guu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3guu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moesziomyces_antarcticus Moesziomyces antarcticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GUU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GUU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3guu| PDB=3guu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3guu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3guu OCA], [https://pdbe.org/3guu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3guu RCSB], [https://www.ebi.ac.uk/pdbsum/3guu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3guu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LIPA_MOEAP LIPA_MOEAP] Hydrolyzes triglycerides, with a preference for substrates with short-chain lengths (C4 to C8). Has the highest activity with tributyrin (C4), followed by tricaproin (C6) and tricaprylin (C8). Can also hydrolyze vinylacetate (C2) and triolein (C18), but with lower efficiency. Has no activity with tripalmitin (C16).<ref>PMID:16575565</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/3guu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3guu ConSurf].
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<div style="clear:both"></div>
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===X-ray structure of Candida Antarctica lipase A===
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==See Also==
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*[[Lipase 3D Structures|Lipase 3D Structures]]
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== References ==
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==About this Structure==
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<references/>
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3GUU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Candida_antarctica Candida antarctica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GUU OCA].
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__TOC__
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[[Category: Candida antarctica]]
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</StructureSection>
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[[Category: Triacylglycerol lipase]]
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[[Category: Large Structures]]
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[[Category: Airenne, T.]]
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[[Category: Moesziomyces antarcticus]]
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[[Category: Brandt, A M.]]
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[[Category: Airenne T]]
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[[Category: Kanerva, L T.]]
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[[Category: Brandt A-M]]
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[[Category: Li, X G.]]
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[[Category: Kanerva LT]]
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[[Category: Nymalm-Rejstrom, Y.]]
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[[Category: Li X-G]]
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[[Category: Salminen, T A.]]
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[[Category: Nymalm-Rejstrom Y]]
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[[Category: Candida]]
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[[Category: Salminen TA]]
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[[Category: Hydrolase]]
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[[Category: Lipase]]
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[[Category: Protein structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:49:16 2010''
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Current revision

X-ray structure of Candida Antarctica lipase A

PDB ID 3guu

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