3a14

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:59, 13 March 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3a14.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of DXR from Thermotoga maritima, in complex with NADPH==
-
The line below this paragraph, containing "STRUCTURE_3a14", creates the "Structure Box" on the page.
+
<StructureSection load='3a14' size='340' side='right'caption='[[3a14]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3a14]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A14 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-
{{STRUCTURE_3a14| PDB=3a14 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a14 OCA], [https://pdbe.org/3a14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a14 RCSB], [https://www.ebi.ac.uk/pdbsum/3a14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a14 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DXR_THEMA DXR_THEMA] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a14_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a14 ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of DXR from Thermotoga maritima, in complex with NADPH===
+
==See Also==
-
 
+
*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
3A14 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A14 OCA].
+
[[Category: Large Structures]]
-
[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
+
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
-
[[Category: Noguchi, K.]]
+
[[Category: Noguchi K]]
-
[[Category: Ohsawa, K.]]
+
[[Category: Ohsawa K]]
-
[[Category: Ohtaki, A.]]
+
[[Category: Ohtaki A]]
-
[[Category: Sasaki, Y.]]
+
[[Category: Sasaki Y]]
-
[[Category: Takenoya, M.]]
+
[[Category: Takenoya M]]
-
[[Category: Yajima, S.]]
+
[[Category: Yajima S]]
-
[[Category: Yohda, M.]]
+
[[Category: Yohda M]]
-
[[Category: Isoprene biosynthesis]]
+
-
[[Category: Mep pathway]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Nadp]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Reductoisomerase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:44:30 2010''
+

Current revision

Crystal structure of DXR from Thermotoga maritima, in complex with NADPH

PDB ID 3a14

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3a14"
Personal tools