1dn7

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[[Image:1dn7.png|left|200px]]
 
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==THE CRYSTAL STRUCTURE OF D(*G-G-G-G-C-C-C-C). A MODEL FOR POLY(D*G)(DOT)POLY(D*C)==
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The line below this paragraph, containing "STRUCTURE_1dn7", creates the "Structure Box" on the page.
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<StructureSection load='1dn7' size='340' side='right'caption='[[1dn7]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DN7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dn7 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1dn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dn7 ProSAT]</span></td></tr>
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</table>
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{{STRUCTURE_1dn7| PDB=1dn7 | SCENE= }}
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the DNA oligomer d(G-G-G-G-C-C-C-C) has been determined at a resolution of 2.5 A by single-crystal X-ray methods. There are two strands in the asymmetric unit, and these coil about each other to form a right-handed double-helix of the A-type with Watson-Crick hydrogen bonds between base-pairs. The helix has a shallow minor groove and a deep, water-filled major groove; almost all exposed functional groups on the DNA are hydrated, and 106 ordered solvent molecules have been found. The two d(G-G-G-G).d(C-C-C-C) segments in the octamer exhibit similar and uniform structures, but there is a slight discontinuity at the GpC step between them. A recurring feature of the structure is the overlap of adjacent guanine bases in each GpG step, with the five-membered ring of one guanine stacking on the six-membered ring of its neighbour. There is little or no overlap between adjacent cytosine rings. Conformational parameters for these GpG steps are compared with those from other single-crystal X-ray analyses. In general, GpG steps exhibit high slide, low roll and variable twist. Models for poly(dG).poly(dC) were generated by applying a simple rotation and translation to each of the unmodified d(G-G-G-G).d(C-C-C-C) units. Detailed features of these models are shown to be compatible with various assays of poly(dG).poly(dC) in solution, and are useful in understanding the polymorphic behaviour of this sequence under a variety of experimental conditions.
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===THE CRYSTAL STRUCTURE OF D(*G-G-G-G-C-C-C-C). A MODEL FOR POLY(D*G)(DOT)POLY(D*C)===
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The crystal structure of d(G-G-G-G-C-C-C-C). A model for poly(dG).poly(dC).,McCall M, Brown T, Kennard O J Mol Biol. 1985 Jun 5;183(3):385-96. PMID:4020865<ref>PMID:4020865</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_4020865}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1dn7" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 4020865 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_4020865}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Theoretical Model]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DN7 OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:4020865</ref><references group="xtra"/>
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[[Category: Brown, T]]
[[Category: Brown, T]]
[[Category: Kennard, O]]
[[Category: Kennard, O]]
[[Category: Mccall, M J]]
[[Category: Mccall, M J]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:00:58 2010''
 

Current revision

Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

THE CRYSTAL STRUCTURE OF D(*G-G-G-G-C-C-C-C). A MODEL FOR POLY(D*G)(DOT)POLY(D*C)

PDB ID 1dn7

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