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1o0j

From Proteopedia

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{{Theoretical_model}}
{{Theoretical_model}}
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{{Seed}}
 
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[[Image:1o0j.png|left|200px]]
 
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==HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE==
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The line below this paragraph, containing "STRUCTURE_1o0j", creates the "Structure Box" on the page.
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<StructureSection load='1o0j' size='340' side='right'caption='[[1o0j]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O0J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o0j FirstGlance], [https://www.ebi.ac.uk/pdbsum/1o0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o0j ProSAT]</span></td></tr>
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</table>
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{{STRUCTURE_1o0j| PDB=1o0j | SCENE= }}
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Sequence alignment of human T-lymphotropic virus type I (HTLV-I) protease and other retroviral proteases reveals that the leukemia virus proteases contain residues at the C-terminus that are absent in the other proteases. We have prepared a mutant of HTLV-I protease that does not contain the 10 C-terminal residues and demonstrated that the catalytic efficiency of cleavage of a peptide substrate is unaffected.
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===HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE===
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The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity.,Herger BE, Mariani VL, Dennison K, Shuker SB Biochem Biophys Res Commun. 2004 Aug 6;320(4):1306-8. PMID:15303275<ref>PMID:15303275</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<!--
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_15303275}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1o0j" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15303275 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15303275}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Theoretical Model]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0J OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:15303275</ref><references group="xtra"/>
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[[Category: Dennison, K]]
[[Category: Dennison, K]]
[[Category: Herger, B E]]
[[Category: Herger, B E]]
[[Category: Shuker, S B]]
[[Category: Shuker, S B]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:05:34 2010''
 

Current revision

Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE

PDB ID 1o0j

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OCA

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