1ige

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{{Theoretical_model}}
{{Theoretical_model}}
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{{Seed}}
 
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[[Image:1ige.png|left|200px]]
 
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==A MODEL OF THE FC OF IMMUNOGLOBULIN E==
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The line below this paragraph, containing "STRUCTURE_1ige", creates the "Structure Box" on the page.
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<StructureSection load='1ige' size='340' side='right'caption='[[1ige]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IGE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ige FirstGlance], [https://www.ebi.ac.uk/pdbsum/1ige PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ige ProSAT]</span></td></tr>
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</table>
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{{STRUCTURE_1ige| PDB=1ige | SCENE= }}
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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A model of the Fc of human IgE was constructed using the known three-dimensional structure of IgG Fc. On the basis of amino acid sequence homology, the CE2, CE3 and CE4 domains were modelled after CG3, CG2 and CG3, respectively. The mode of association of the CG2 and of the CG3 pairs of domains was assumed for the CE3 and the CE4 pairs, respectively; the CE2 pair of domains was assembled such that they interact like the CG3 domains. An asymmetric linkage is favored for the two inter-epsilon chain disulfide bridges, i.e. the bonds were assumed to be between non-homologous cysteines. The atomic interactions in the interface of the CE2:CE2 and CE4:CE4 domain pairs were computed, and predictions are made on the solvent accessibility of the individual residues in the fragment. The model can be useful in the study of regions that may be involved in the interaction of IgE with Fc(epsilon) receptors.
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===A MODEL OF THE FC OF IMMUNOGLOBULIN E===
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A model of the Fc of immunoglobulin E.,Padlan EA, Davies DR Mol Immunol. 1986 Oct;23(10):1063-75. PMID:3796618<ref>PMID:3796618</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_3796618}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1ige" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 3796618 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_3796618}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Theoretical Model]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IGE OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:3796618</ref><references group="xtra"/>
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[[Category: Davies, D R]]
[[Category: Davies, D R]]
[[Category: Padlan, E A]]
[[Category: Padlan, E A]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:33:48 2010''
 

Current revision

Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

A MODEL OF THE FC OF IMMUNOGLOBULIN E

PDB ID 1ige

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