2a12

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{{Theoretical_model}}
{{Theoretical_model}}
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{{Seed}}
 
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[[Image:2a12.png|left|200px]]
 
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==THEORETICAL MODEL OF THE AI5G GROUP II INTRON==
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The line below this paragraph, containing "STRUCTURE_2a12", creates the "Structure Box" on the page.
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<StructureSection load='2a12' size='340' side='right'caption='[[2a12]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A12 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a12 FirstGlance], [https://www.ebi.ac.uk/pdbsum/2a12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a12 ProSAT]</span></td></tr>
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</table>
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{{STRUCTURE_2a12| PDB=2a12 | SCENE= }}
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Despite the biological importance of self-splicing group II introns, little is known about their structural organization. Synthetic incorporation of site-specific photo-cross-linkers within catalytic domains resulted in functional distance constraints that, when combined with known tertiary interactions, provide a three-dimensional view of the active intron architecture. All functionalities important for both steps of splicing are proximal before the first step, suggestive of a single active-site region for group II intron catalysis.
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===THEORETICAL MODEL OF THE AI5G GROUP II INTRON===
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A single active-site region for a group II intron.,de Lencastre A, Hamill S, Pyle AM Nat Struct Mol Biol. 2005 Jul;12(7):626-7. Epub 2005 Jun 26. PMID:15980867<ref>PMID:15980867</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_15980867}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2a12" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15980867 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15980867}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Theoretical Model]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A12 OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:15980867</ref><references group="xtra"/>
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[[Category: De Lencastre, A]]
[[Category: De Lencastre, A]]
[[Category: Hamill, S]]
[[Category: Hamill, S]]
[[Category: Pyle, A M]]
[[Category: Pyle, A M]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:59:14 2010''
 

Current revision

Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

THEORETICAL MODEL OF THE AI5G GROUP II INTRON

PDB ID 2a12

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