1k5y

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{{Theoretical_model}}
{{Theoretical_model}}
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{{Seed}}
 
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[[Image:1k5y.png|left|200px]]
 
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==STRUCTURE OF THE TRANSLATING 80S RIBOSOME FROM YEAST, OBTAINED BY DOCKING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO A 15A CRYO-EM MAP. THIS FILE 1K5Y CONTAINS THE 60S RIBOSOMAL SUBUNIT. THE FILE 1K5X CONTAINS THE 40S RIBOSOMAL SUBUNIT, THE P-SITE BOUND TRNA AND THE MRNA CODON.==
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The line below this paragraph, containing "STRUCTURE_1k5y", creates the "Structure Box" on the page.
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<StructureSection load='1k5y' size='340' side='right'caption='[[1k5y]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K5Y FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k5y FirstGlance], [https://www.ebi.ac.uk/pdbsum/1k5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k5y ProSAT]</span></td></tr>
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</table>
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{{STRUCTURE_1k5y| PDB=1k5y | SCENE= }}
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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A cryo-EM reconstruction of the translating yeast 80S ribosome was analyzed. Computationally separated rRNA and protein densities were used for docking of appropriately modified rRNA models and homology models of yeast ribosomal proteins. The core of the ribosome shows a remarkable degree of conservation. However, some significant differences in functionally important regions and dramatic changes in the periphery due to expansion segments and additional ribosomal proteins are evident. As in the bacterial ribosome, bridges between the subunits are mainly formed by RNA contacts. Four new bridges are present at the periphery. The position of the P site tRNA coincides precisely with its prokaryotic counterpart, with mainly rRNA contributing to its molecular environment. This analysis presents an exhaustive inventory of an eukaryotic ribosome at the molecular level.
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===STRUCTURE OF THE TRANSLATING 80S RIBOSOME FROM YEAST, OBTAINED BY DOCKING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO A 15A CRYO-EM MAP. THIS FILE 1K5Y CONTAINS THE 60S RIBOSOMAL SUBUNIT. THE FILE 1K5X CONTAINS THE 40S RIBOSOMAL SUBUNIT, THE P-SITE BOUND TRNA AND THE MRNA CODON.===
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Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.,Spahn CM, Beckmann R, Eswar N, Penczek PA, Sali A, Blobel G, Frank J Cell. 2001 Nov 2;107(3):373-86. PMID:11701127<ref>PMID:11701127</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_11701127}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1k5y" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 11701127 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_11701127}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Theoretical Model]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K5Y OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:11701127</ref><references group="xtra"/>
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[[Category: Beckmann, R]]
[[Category: Beckmann, R]]
[[Category: Blobel, G]]
[[Category: Blobel, G]]
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[[Category: Sali, A]]
[[Category: Sali, A]]
[[Category: Spahn, C M.T]]
[[Category: Spahn, C M.T]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:28:38 2010''
 

Current revision

Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

STRUCTURE OF THE TRANSLATING 80S RIBOSOME FROM YEAST, OBTAINED BY DOCKING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO A 15A CRYO-EM MAP. THIS FILE 1K5Y CONTAINS THE 60S RIBOSOMAL SUBUNIT. THE FILE 1K5X CONTAINS THE 40S RIBOSOMAL SUBUNIT, THE P-SITE BOUND TRNA AND THE MRNA CODON.

PDB ID 1k5y

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