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3idw

From Proteopedia

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{{Seed}}
 
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[[Image:3idw.png|left|200px]]
 
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==Crystal structure of Sla1 homology domain 2==
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The line below this paragraph, containing "STRUCTURE_3idw", creates the "Structure Box" on the page.
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<StructureSection load='3idw' size='340' side='right'caption='[[3idw]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3idw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IDW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IDW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3idw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3idw OCA], [https://pdbe.org/3idw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3idw RCSB], [https://www.ebi.ac.uk/pdbsum/3idw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3idw ProSAT]</span></td></tr>
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{{STRUCTURE_3idw| PDB=3idw | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of Sla1 homology domain 2===
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[https://www.uniprot.org/uniprot/SLA1_YEAST SLA1_YEAST] Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.<ref>PMID:8335689</ref> <ref>PMID:8756649</ref> <ref>PMID:9008707</ref> <ref>PMID:9128251</ref> <ref>PMID:10198057</ref> <ref>PMID:10594004</ref> <ref>PMID:11940605</ref> <ref>PMID:11950888</ref> <ref>PMID:12388763</ref> <ref>PMID:12237851</ref> <ref>PMID:12814545</ref> <ref>PMID:12734398</ref> <ref>PMID:14761940</ref> <ref>PMID:15525671</ref> <ref>PMID:17286805</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 20150898 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/3idw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_20150898}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3idw ConSurf].
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3IDW is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IDW OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:20150898</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Bowie, J U.]]
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[[Category: Bowie JU]]
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[[Category: Cascio, D.]]
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[[Category: Cascio D]]
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[[Category: Payne, G S.]]
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[[Category: Di Pietro SM]]
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[[Category: Pietro, S M.Di.]]
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[[Category: Payne GS]]
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[[Category: Actin-binding]]
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[[Category: Cell membrane]]
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[[Category: Clathrin adaptor]]
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[[Category: Cytoplasm]]
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[[Category: Cytoskeleton]]
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[[Category: Endocytosis]]
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[[Category: Endosome]]
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[[Category: Membrane]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Sam domain]]
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[[Category: Sh3 domain]]
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[[Category: Yeast]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 08:58:53 2010''
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Current revision

Crystal structure of Sla1 homology domain 2

PDB ID 3idw

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