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2kvg

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{{Seed}}
 
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[[Image:2kvg.jpg|left|200px]]
 
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==Structure of the three-Cys2His2 domain of mouse testis zinc finger protein==
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The line below this paragraph, containing "STRUCTURE_2kvg", creates the "Structure Box" on the page.
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<StructureSection load='2kvg' size='340' side='right'caption='[[2kvg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2kvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KVG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2kvg| PDB=2kvg | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kvg OCA], [https://pdbe.org/2kvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kvg RCSB], [https://www.ebi.ac.uk/pdbsum/2kvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kvg ProSAT]</span></td></tr>
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</table>
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===Structure of the three-Cys2His2 domain of mouse testis zinc finger protein===
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== Function ==
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[https://www.uniprot.org/uniprot/ZBT32_MOUSE ZBT32_MOUSE] DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.<ref>PMID:11279021</ref>
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== References ==
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==About this Structure==
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<references/>
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2KVG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVG OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Chen, C.]]
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[[Category: Chen C]]
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[[Category: Chou, C C.]]
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[[Category: Chou C-C]]
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[[Category: Lou, Y C.]]
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[[Category: Lou Y-C]]
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[[Category: Metal-binding]]
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[[Category: Protein/dna]]
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[[Category: Transcription]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 14 09:46:46 2010''
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Current revision

Structure of the three-Cys2His2 domain of mouse testis zinc finger protein

PDB ID 2kvg

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